Friday 14th SATELLITE SYMPOSIUM

Roni Lara Moya

Title: Regenerative Biomedicine and Xenogeneic Cell Therapy in Immune              Rejuvenation

Abstract: 

With aging comes a remodeling of the immune system. Over time, this leads to a decline in immune effectiveness, resulting in increased vulnerability to infectious diseases, decreased vaccination responses, and susceptibility to age-related inflammatory diseases. This phenomenon, called immunosenescence, is multifactorial and affects both natural and acquired immunity. As aging is a plastic process, it is influenced by both nutritional and pharmacological interventions. Regenerative biomedicine aims to use cutting-edge technology specialized in cell therapy and tissue-derived peptides; as well as their regenerative factors to combat immunosenescence and rejuvenate the immune system. The purpose of this conference is to develop the basic concepts on cell therapy in biomedical clinical practice for immune rejuvenation.

Short bio:  

Roni Lara Moya Is an immunologist with specialization in Anti-aging and Regenerative Medicine. Professor and Scientific Investigator at the International University of BioRegenerative Sciences (IUBRS) in the- United States, a Biomedical Consultant of the EuropeanWellness Academy (EWA), as well as an Executive and Scientific Director of Regenera – Regenerative Biomedicine; Lisbon

(2nd Talk)

Title: Mitochondrial Cell Therapy in Anti-Aging Practice

Abstract: 

Mitochondrial degeneration has been shown to be the major cause of age-related deterioration and scientific reports concluded that the tissues of a 70-year-old man contained 95% damaged mitochondria compared to almost no damage in that of a 5- year-old child. Hundreds of scientific papers link defective mitochondria to virtually all degenerative diseases such as Alzheimer’s, diabetes, cardiovascular disease, obesity and cancer. Cell therapy is a regenerative biomedical treatment based on the combination of peptides, amino acids, proteins, growth factors, transcription factors and hormones derived from cellular tissues with the aim of biochemical, metabolic and immunological modulation as well as cellular restoration. Being a fusion of cell therapy and mitochondrial medicine, mitochondrial organelle cell therapy includes a range of peptides that broadens the horizons of therapeutic rejuvenation and creates new opportunities for aesthetic and anti-aging practitioners. Mitochondrial peptides contain an immaculate blend of cellular peptides, predominantly specific to mitochondria, extracted to ensure rapid cell regeneration and restoration of normal function. The aim of this talk is to present the potential for clinical use of mitochondrial cell peptides in anti-aging and regenerative practice.

Prof. Mike Chan

Title: Non-Invasive and Painfree Stem cell Peptides for Hair Loss, Face, Neck, V-Line & Hands

Abstract: 

HFR (Hair Follicles Regenerator) is a stem cell peptide used to prevent hair loss and revitalize the hair follicles for hair restoration and scalp rejuvenation. It is a new innovative treatment that allows the end consumer to perform the treatment at home safely without the risk of skin infection, allergy, or irritation. HFR can be applied onto the scalp by using the MicroNed Stamper that helps to delivers the bioactive peptides to the hair follicles and stimulate the production of progenitor cells in hair follicles. Cellular Peptides Nano in aesthetic range designed with the highest quality peptides molecules and cellular extracts prepared from precursor stem cells. The small molecular size of peptides allows a higher bioavailability rate for aesthetic purposes. The Cellular Peptides Nano is made of organ-specific cellular extracts. Using the MicroNed Stamper is also an effective way to smoothen the skin and removing rhytides (fine lines). By stimulating collagen and elastin production and repairing skin from the inside, your skin will stay beautiful even as you get older. MicroNed Stamper also works well with Cellular Peptide Nano.

Short bio:  

Prof. Mike Chan, is a Founder of European Wellness Biomedical Group, Germany. An Author/co-author of over 30 books with over 60 scientific and medical publications. He won multiple international invention awards for Biotechnology and holds multiple international patents in stem cells immunology & biotech. He sits on the Board & heads the Scientific Committee for Regenerative Medicine, European Society of Preventative, Regenerative and Anti-Aging Medicine and the Society’s Asian Chairman; an Associate Professor of the American Academy of Stem Cell Physicians), and Chairman of the American Academy of Anti-Aging Medicine for Thailand. He is Chairman of Japan’s Medical Association for Regenerative Medicine, Senator of BWA, Germany (Federal Association for Economic Development & Foreign Trade for China, Indonesia & Malaysia). He spearheads, hires, and works in collaboration with top scientists and scholars worldwide from MIT, Oxford, Cambridge Heidelberg University, and University of Irvine, California, etc. He won numerous awards (17), for top leadership, entrepreneurship, quality assurance, and achievement awards from Europe to China and holds membership in more than 20 academic bodies and associations.

2nd Talk

Title: The future potential of stem cells and peptides for age reversal in precision medicine

Abstract: 

The functions of progenitor (precursor) stem cells is based on two principles – “homing” and paracrine effect. The mechanism of action of organ-specific peptide therapy is based on molecular self-organization and trans-membrane peptide transport and re-assembly according to the intrinsic factors – zip-codes encoded in each chain of peptides. Xenogeneic transplantation is also working through the epigenetic influence on the gene-expression of the implanted cell material. The part of the phenotypes that is not visible can be observed in biochemical assays. It means that in cell therapy, when fetal cell of xenogeneic origin is implanted to the human body, it is the environment that dictates and determines how exactly the cell should function. Xenotransplantation became a potential alternative to the whole organ transplant and treatment of many degenerative diseases, which are considered incurable from the point of view of conventional medicine – chronic liver disease, early stages of renal failure, post ischemic stroke, neurologic deficit, Parkinson’s disease, Autism, certain genetic abnormalities and congenital diseases. Xenogeneic cellular therapy products have multiple advantages, such as unlimited cell supply, high metabolic similarities to humans, low risk of acute vascular rejection, resistance to complement-mediated injury, and resistance to retroviruses.

Prof. Dr. Thomas Skutella (Heidelberg Uni)

Title: A stress-induced cellular anti-aging model of fetal stem-cell peptides of Mito Organelles from lung and placenta on HEK and HEPG2 cells in senescence in vitro model

Abstract:
Aging refers to the physical and functional decline of the tissues over time that often leads to age-related degenerative diseases. We have utilized a model of stress-induced senescence (Hydrogen peroxide treatment protocol) and effectively induced HEK and HepG2 cells to undergo cellular senescence as determined by augmented senescence-associated-b-galactosidase (SA-b-gal) staining, decreased proliferation and differentiation capacity and elevated reactive oxygen species (ROS) level. The phenotypic changes were accompanied by a significant increase in p16, p21, and p53 expression and a decreased expression of critical proteins in various DNA repair pathways. Treatment of the cells during stress-induced senescence significantly with Mito Organelles (MO) characterized by proteomics from the placenta and lung reduced all markers of cellular senescence in HEK and HepG2 cells. Taken together, we have successfully demonstrated the functional impact of MOs within a molecular exploration of senescence and aging in vitro.

Short Bio:
Prof. Dr. Thomas Skutella (Heidelberg Uni)

Dr. Joel Osorio

Title: A possible neuroregeneration on ASIA-A scale using a Medtronic Neurostimulator and combinatorial biologics: Bioquantine® and Wharton’s Jelly Mesenchymal Stem Cells as standardized therapy for No Option patients.

Abstract: 

The use of our combinatorial biologics based in the combination of a unique polypeptide (Bioquantine®) and Wharton’s Jelly or Umbilical Cord Mesenchymal Stem Cells (UCMSCs) specifically Wharton’s Jelly derivate ones represents one of the most important and promising and now safe and tested strategy to stimulate the neuroregeneration. In this review, the therapeutic role of MSCs is discussed, together with their properties, application, limitations, and future perspectives. An array of mesenchymal stem cells (MSCs) from various sources with novel and promising strategies are being developed to improve function after SCI. We briefly discuss the pathophysiology of spinal cord injuries and characteristics and the potential sources of MSCs that can be used in the treatment of SCI. Our evidence and science based method is showing a promising alternative on the ASIA-A classification SCI. Added to it, we utilized an improved delivery method (making it ambulatory) for the in situ application of subdural Wharton’s Jelly MSCs and a unique polypeptide (Bioquantine®). Thereafter we proceeded with the intrathecal application of an advanced neurostimulator biomedical system obtaining improved results and faster clinical recovery after only 5 weeks of the started translational protocol.

Short Bio:

Dr. Osorio is an innovative businessman with a distinct entrepreneurial mindset concentrated in adding value on the areas of Biotechnology (mRNA), Reprogramming & Regenerative Medicine for translational use in humans. Chariman at REGENERAGE® Clinic and its Initiatives. VP and Clinical Developer for Bioquark,Inc. President at Dr. Jois®, VP and Chairman of the WAMS Americas Division. Earned MD degree at Westhill University. Diplomate in aesthetic medicine (UAG), Advance Fellow by the ABAARM, visiting scholar at UNC at Chapel Hill in Dermatology. Fellow in Stem Cell Medicine by the A4M and USF, Business Diplomate at ECA, enrolled Master on Health Sciences at Victoria University. Has appeared on several occasions on International media. A lecturer and keynote speaker in more than 30 international conferences and congresses makes him a leader on the Regenerative & Reprogramming Medicine Field.

Prof. Ursula Jacob 

Title: Corona virus -New diagnostics and therapy options

Abstract: 

I will report about the different forms of diagnostics of corona virus. We already know from different publications that this virus can damage the nervous system, the immune system etc. We could show in testing miRNA of corona, which specific damage for now and later this virus can cause and we will show as well how it can trigger other viruses from herpes group. In addition, will discuss the reasons why post – Covid and long – Covid is increasing. Out of this knowledge we can treat the patients individually for their needs.

Dr. Robert Baring, Member I-GAP and President of Association for Functional Medicine.

Title: The genius of Nrf2

Michelle Passarge, Biovis Diagnostik.

Title: Cleaning the teeth and the oral cavity-The first step in Anti-Aging Medicine

Prof. Tilman Fritsch

Title: Cleaning the teeth and the oral cavity-The first step in Anti-Aging Medicine